Dermatological problems in kidney recipients in Yazd Province, Iran

Kidney transplantation is one of the effective methods to treat kidney disease. In a kidney transplant, due to the use of many immunosuppressive drugs, the body is often subjected to various benign, premalignant and malignant dermatoses. The early diagnosis and effective treatment of such conditions can potentially reduce morbidity and mortality. To determine the distribution of dermatoses in patients who have received kidney transplants. This cross-sectional study was performed on 120 kidney transplant recipients in Yazd University Hospitals in two years. The patients were examined by a dermatologist and diagnosis was made on the basis of clinical observations. Biopsies and scraping of the lesions were taken whenever necessary. 120 evaluable patients included 84 males and 36 females with mean age of 32 years. A total of 116 patients developed dermatological symptoms, which included: hypertrichosis [78.3%], photosensitivity [70%], cushingoid face [60%], gingival hyperplasia [43.3%], warts [40%], pityriasis versicolor [33.3%], steroidal acne [26.6%], herpes simplex [13.3%] herpes zoster [10%], nonmelanoma cancer [10%], oral candidiasis [6.6%], striae [6.6%], actinic keratosis [6.6%] and sebaceous hyperplasia [3.3%]. Skin lesions are a significant problem in kidney transplant recipients. A careful monitoring of these patients is recommended in order to detect these lesions in early stages and treat them

Pattern of skin diseases in the central Iran, Yazd Province

The pattern of skin diseases differs from region to region based on geographical, racial and cultural circumstances. For the purpose of education and reeducation of physicians, it is necessary to have knowledge of the conditions and distribution of diseases. To elicit pattern of common skin diseases in the region of Central Iran, Yazd Province. Two separate descriptive studies were conducted in order to analyze the dermatoses seen in outpatients and inpatients at the Dermatology Department, Shahid Sadoughi Medical Science University, Yazd, Iran. Patient files who visited the dermatologists were reviewed. Diagnosis was coded, categorized, discussed and analyzed according to International Classification of Diseases, revision 10 [ICD-10]. Skin infections with 23.4% were the most common cause of referral to dermatology outpatients, followed by dermatitis 19.2%, acne 10.8%, melasma 7.8% and urticaria 5.3%. Melasma in women and psoriasis in men were significantly more common. In inpatient group skin infections were the most common 34.3%, followed by dermatitis 13.2%, drug reactions 11.2%, psoriasis 9.6% and malignant tumors. Psoriasis was significantly more common in men and viral infections [herpes zoster] in women. The high occurrence rate of skin infections and dermatitis in our study population requires further study in order to pinpoint its root causes. Improving the socio-economic status, environmental and personal hygiene, as well as specific instruction to the at-risk group can be beneficial

[Acanthosis nigricans, tripe palms and leser-trelat sign in patient with carcinoid tumor]

Acanthosis nigricans [AN], Tripe palm [TP] and sign of lesser trelat [LT] are rare dermatoses which are often seen with malignant conditions. Acanthosis nigricans occurs both on the skin and mucus membranes as velvety hyper pigmented lesions in the flexors and around the neck, or papillomatous and verrucous lesions on the lips and buccal mucosa. These para neoplastic dermatoses are generally linked with intra - abdominal malignancies, especially gastric adenocarcinomas and improvement of the associated dermatoses after treatment of the malignancy has been frequently observed, although it has also been observed with other malignancies. We report the case of a 44 year old woman who initially came to be treated for her mucocutaneous lesions, and with diagnosis of malignant AN was further studied for the initial malignancy and finally, her main malignancy was determined as carcinoid tumor

[Four cases of angular cheilitis in orthodontic patients]

Contact dermatitis is an inflammatory reaction of the skin and mucosa to either external or internal factors. It can be divided to two forms of irritant contact dermatitis and allergic contact dermatitis. Nickel is one of the most common materials that causes allergic contact dermatitis and is widely used in orthodontic appliances. The inflammatory reaction to this metal in orthodontics is usually stomatitis and angular cheilitis is very rare. We report 4 cases of angular cheilitis in orthodontic patients and discuss about their causes and treatments